Wear tests were performed with PTFE+Al2O3 nanocomposites on various manufactured surfaces to determine whether or not the wear resistance of these nanocomposites is a strong function of surface preparation. Grade 304 stainless steel counterfaces having four different surface finishes were used: electropolished (Rq 88 nm), lapped (Rq 161 nm), wet-sanded (Rq 390 nm), and dry-sanded (Rq 578 nm). PTFE+Al2O3 nanocomposites made from powders of roughly 2-20 um PTFE (matrix) and ~44 nm Al2O3 (filler) were prepared at filler weight percentages of 0%, 1%, 5% and 10% and tested on each surface finish. Additionally, 5 wt.% 44 nm nanocomposites were compared to identically prepared 5 wt.% 80 nm and 500 nm Al2O3 filled PTFE composites on each surface. Friction coefficients were between 0.12 and 0.19 and wear rates decreased from K=810x10-6 mm3/Nm for the 5 wt.% 500 nm alumina filled PTFE on the dry-sanded surface to K=0.8x10-6 mm3/Nm for the 5 wt.% 80 nm filled composite on the lapped surface. It was found that the minimum wear rate occurred on the lapped counterface for every composite, and the wear-rate is a strong function of the transfer film thickness and morphology.