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| AGR 3303 (3 credits) University of Florida - Fort Lauderdale |
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| Below is exam #2 for 1993, Mendelian genetics |
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AGR 3303 - Genetics 1 Nov 1993 University of Florida - Fort Lauderdale Exam #1: PARTICULATE GENETICS Name ________________________________________
Multiple choice (45 pts) Read these carefully. One and only one response (a, b, c, d, or e) completely and correctly answers the question, or completes the statement. Circle the appropriate response and turn in this exam. Please make sure your circle is unambiguous. 1. In an organism that is 2n=8, the drawing below most accurately depicts:
a. mitosis b. first division of meiosis c. second division of meiosis d. interphase e. cannot be determined 2. In Andalusian fowls, blue is the heterozygous condition of the alleles for black plumage, B, and white, b. A black Andalusian bird is mated to a white bird and the F1 is mated to a blue bird. What proportion of the progeny will be white? a. 0 b. 1/4 c. 2/4 d. 3/4 e. 1 3. In horses, the Palomino color is the result of incomplete dominance at the C locus. The homozygous C1C1 is albino and the homozygous C2C2 is chestnut. What phenotypic ratio would be expected from mating of two Palomino horses? a. 9:3:3:1 b. 3:1 c. 1:2:1 d. 1:1 e. all Palomino 4. Hemophilia in humans is a sex-linked recessive trait. A woman has two biological sons, #1 and #2. Son #1 has hemophilia. We can be sure that: a. son #2 must also have hemophilia b. the father of son #1 must have hemophilia c. the mother must have hemophilia d. there is a 50% chance that son #2 has hemophilia e. there is a 25% chance that son #2 has hemophilia 5. In the following metabolic pathway for anthocyanin (purple coloration) the enzymes A and B are coded for by the dominant alleles at the gene loci A and B, respectively. The A and B loci are not linked, but assort independently. What would be the frequency of green (purple deficient) progeny from the cross AAbb X aaBB? enzyme A enzyme B anthocyanin ® anthocyanin ® anthocyanin (purple) precursor (green) intermediate (green) a. 100% b. 50% c. 25% d. 12.5% e. 0% 6. A plant with the chromosome constitution AABBCCDD would be an: a. allotetraploid b. autohexaploid c. allooctoploid d. autotetraploid e. all of the above 7. Which relationship is correct? a. the zygote is haploid, the gamete is diploid b. the zygote is diploid, the gamete is haploid c. the zygote and the gamete are diploid d. the zygote and the gamete are haploid e. none of the above 8. A twenty-year-old's mother died from Huntington's disease, which is caused by a dominant allele. What is the probability that this 20-year-old inherited the disease? a. 0% b. 25% c. 50% d. 75% e. 100% 9. A chi-square was calculated from a genetics experiment, based on a comparison of observed phenotypes with their expected distribution based on Mendelian genetics. The tabular probability level for chi-square was P < 0.00001, thus we conclude that: a. the null hypothesis cannot be accepted b. Mendelian genetics does not adequately explain the results c. we might have miscounted or misclassified fruit flies d. all of the above e. none of the above 10. A woman of blood type O has a child of blood O. Four men were suspected of being the father of the child. The blood types of each of the four men were AB, A, B, and O. We can conclude that: a. any of the four men could have fathered the child b. only the man of type AB could not have been the father c. only the man of type O could have been the father d. only the men of types A and B could not have been the father e. the men of types A, B, and AB could not have been the father 11. Coat color in dogs depends on the action of at least two genes. At one locus a dominant epistatic inhibitor of coat color pigment (I_) prevents the expression of color alleles at another independently assorting locus, thereby producing white coat color. When the recessive condition exists at the inhibitor locus (ii), the alleles of the second locus will be expressed, iiB_ producing black and iibb producing brown. When dihybrid white dogs are mated, what would be the phenotypic ratio in the offspring? a. 12:3:1 b. 9:7 c. 9:3:3:1 d. 3:1 e. 1:2:1 12. Alleles may be described as a. alternative forms of two different loci b. similar forms of two different loci c. alternative forms of a single gene d. similar forms of a single gene e. all of the above 13. A variegated Anthurium plant is found by a foliage breeder. The breeder crosses this plant with a normal all-green Anthurium and obtains a variegated F1. The F2 segregates 3 variegated:1 green. The mutant trait is a. dominant to green and controlled by two independent alleles b. incompletely dominant to green and controlled by a single gene c. recessive to green and controlled by a single gene d. dominant to green and controlled by a single gene e. more crosses must be made to determine the mode of inheritance 14. In the following metabolic pathway for anthocyanin (purple coloration) the functional enzymes A and B are coded for by the dominant alleles at the gene loci A and B, respectively. The loci for A and B are not linked, thus they assort independently. What would be the phenotypic frequency of green (purple deficient) progeny from the cross AaBb X aabb? enzyme A enzyme B anthocyanin ® anthocyanin ® anthocyanin (purple) precursor (green) intermediate (green) a. 100% b. 50% c. 25% d. 0% e. cannot be determined 15. Calico cats are always female because: a. the maternal X chromosome is always heterochromatized into a Barr body b. either the maternal or paternal X chromosome is randomly inactivated at an early stage of development c. either the maternal or paternal X chromosome is heterochromatized so all cells throughout the calico cat have the same inactivated chromosome d. she always receives her X chromosomes from her mother, which may also be calico e. none of the above
Matching (30 pts.) In each of the following ten blank spaces, insert the correct word or phrase from the following list: codominance continuous variation epistasis homozygosity independent assortment mitosis polyploidy product law sex linkage trisomy 16. Recessive alleles are expressed only when they occur in a condition of
__________________________________. 17. The condition of having more than two sets of chromosomes is
__________________________________. 18. Most genetic traits are believed to be controlled by many genes; this results in a phenotypic pattern of __________________________________. 19. In class we observed albino sorghum seedlings in a frequency of 7/16. This is evidence that the albino phenotype is controlled by two genes interacting in a nonreciprocal manner, that is, one gene masks the potential effect of the other gene. This interaction is called __________________________________. 20. The gene for white eyes in fruit flies is on the X chromosome; this is an example of
__________________________________. 21. In human blood types the alleles coding for the A antigen and the B antigen are related by
__________________________________. 22. Virtually all the cells of your body are genetically identical, because they were produced by a process of identical cell division called __________________________________.
23. The __________________________________ holds that the probability of two independent events occurring simultaneously is found by multiplying their independent probabilities.
24. Down syndrome is the only human autosomal _________________________________ in which a significant number of individuals survives longer than one year past birth. 25. During meiosis, homologous chromosomes are reshuffled in a random manner called
__________________________________. Short answer (25 pts.) 26. Cystic fibrosis is caused by a single autosomal recessive gene. A woman and a man have a child with cystic fibrosis; the child dies when she is eight years old. The couple want to have another child, and are considering artificially inseminating the woman through a sperm bank located in the Empire State Building. Would this reduce the likelihood that the second child has cystic fibrosis (Yes or No)? Why or why not (what specifically are the probabilities with or without using the sperm bank)? What other information would help you tell the couple more precisely the odds?
Circle: Yes or No
Estimated probability without sperm bank (use the original father's sperm):
Estimated probability with the sperm bank:
Other helpful information needed:
27. Below is the pedigree of the descendants of Victoria, Queen of Great Britain and Empress of India. She is believed to have carried the recessive allele for hemophilia on her X chromosome. (In this figure, females are represented by circles and males by squares; solid squares are hemophiliac males; circles within circles are female carriers, or heterozygotes). According to the chart, Prince Charles does not have hemophilia. If you did not already know this, what would be the likelihood (probability) that he would have hemophilia? Why? (10-20 words or less)
Probability: ___________________
Why?
28. What are three differences which distinguish meiosis from mitosis? Mitosis Meiosis
#1
#2
#3
29. What is the purpose of chi-square analysis (6 to 20 words or less)?
30. A dihybrid cross (e.g., AABB X aabb > F1 AaBb and F1 AaBb X F1 AaBb > F2 ) leads to a phenotypic ratio of 9:3:3:1 (assuming no epistasis). What are the two key processes or relationships that must be present for this to occur? |
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