PAPERS TO READ
Genetics and Aging

 

 
 
 
 
 

Papers to Read
 
 

EXERCISE

NEEHARIKA-INTERNET
Ichikawa M, Fujita Y, Ebisawa H, Ozeki T.
Effects of long-term, light exercise under restricted feeding on age-related changes in physiological and metabolic variables in male Wistar rats.
Mech Ageing Dev. 2000 Jan 24;113(1):23-35.
PMID: 10708247 [PubMed - indexed for MEDLINE]

YOUNG (on the Internet + REVIEW optional)
Venditti P, Masullo P, Di Meo S.
Effect of training on H(2)O(2) release by mitochondria from rat skeletal muscle.
                       Arch Biochem Biophys. 1999 Dec 15;372(2):315-20.
                       PMID: 10600170 [PubMed - indexed for MEDLINE]

Di Meo S, Venditti P.
Mitochondria in exercise-induced oxidative stress.
                       Biol Signals Recept. 2001 Jan-Apr;10(1-2):125-40. Review.
                       PMID: 11223645 [PubMed - indexed for MEDLINE


JOEL  (on the Internet + REVIEW optional)
Vina J, Gimeno A, Sastre J, Desco C, Asensi M, Pallardo FV, Cuesta A, Ferrero JA, Terada LS, Repine JE.
Mechanism of free radical production in exhaustive exercise in humans and rats; role of xanthine oxidase and protection by allopurinol.
IUBMB Life. 2000 Jun;49(6):539-44.
PMID: 11032249 [PubMed - indexed for MEDLINE]

Vina J, Gomez-Cabrera MC, Lloret A, Marquez R, Minana JB, Pallardo FV, Sastre J. Related Articles
Free radicals in exhaustive physical exercise: mechanism of production, and protection by antioxidants.
IUBMB Life. 2000 Oct-Nov;50(4-5):271-7. Review.
PMID: 11327321 [PubMed - indexed for MEDLINE]


MITOCHONDRIAL DELETIONS 

Pesce V, Cormio A, Fracasso F, Vecchiet J, Felzani G, Lezza AM, Cantatore P, Gadaleta MN. DARIN-INTERNET
Age-related mitochondrial genotypic and phenotypic alterations in human skeletal muscle.
Free Radic Biol Med. 2001 Jun 1;30(11):1223-33.
PMID: 11368920 [PubMed - in process]
CALORIC RESTRICTION

Lal SB, Ramsey JJ, Monemdjou S, Weindruch R, Harper ME. MINA-INTERNET
Effects of caloric restriction on skeletal muscle mitochondrial proton leak in aging rats.
J Gerontol A Biol Sci Med Sci. 2001 Mar;56(3):B116-22.
PMID: 11253148 [PubMed - indexed for MEDLINE]

Gredilla R, Sanz A, Lopez-Torres M, Barja G.  JEFF-INTERNET
Caloric restriction decreases mitochondrial free radical generation at complex I and lowers oxidative damage to mitochondrial DNA in
the rat heart. FASEB J. 2001 Jul;15(9):1589-91. PMID: 11427495 [PubMed - indexed for MEDLINE

FREE RADICAL THEORY OF AGING

Ku HH, Brunk UT, Sohal RS. (IN THE BOX ON MY DOOR) IRA
Relationship between mitochondrial superoxide and hydrogen peroxide production and longevity of mammalian species.
Free Radic Biol Med. 1993 Dec;15(6):621-7.
PMID: 8138188 [PubMed - indexed for MEDLINE]


Huang TT, Carlson EJ, Gillespie AM, Shi Y, Epstein CJ. (ON THE INTENET) TOSS -INTERNET
Ubiquitous overexpression of CuZn superoxide dismutase does not extend life span in mice.
 J Gerontol A Biol Sci Med Sci. 2000 Jan;55(1):B5-9.
PMID: 10719757 [PubMed - indexed for MEDLINE]

Carlsson LM, Jonsson J, Edlund T, Marklund SL. TONY-INTERNET
Mice lacking extracellular superoxide dismutase are more sensitive to
hyperoxia.
Proc Natl Acad Sci U S A. 1995 Jul 3;92(14):6264-8.
PMID: 7603981 [PubMed - indexed for MEDLINE]


B. Barja G, Herrero A. (ON THE INTERNET) (ON YOUR OWN)
Oxidative damage to mitochondrial DNA is inversely related to maximum life span in the heart and brain of mammals.
FASEB J. 2000 Feb;14(2):312-8.
PMID: 10657987 [PubMed - indexed for MEDLINE]
TELOMERASE AND TELOMERES

ANDY JUDGE
Rudolph KL, Chang S, Lee HW, Blasco M, Gottlieb GJ, Greider C, DePinho RA.
Longevity, stress response, and cancer in aging telomerase-deficient mice.
Cell. 1999 Mar 5;96(5):701-12.
PMID: 10089885 [PubMed - indexed for MEDLINE

JESS STAIB-INTERNET
Leri A, Malhotra A, Liew CC, Kajstura J, A
Telomerase activity in rat cardiac myocytes is age and gender dependent.
J Mol Cell Cardiol. 2000 Mar;32(3):385-90.
PMID: 10731438 [PubMed - indexed for MEDLINE]
Presentations should be between 20-30 Minutes.
MITOCHONDRIA

Alberts, B, D Bray, J. Lewis, M. Raff, K. Roberts. Molecular Biology of The Cell. Third edition, Garland, 1994.1. Alberts, B, D Bray, J. Lewis, M. Raff, K. Roberts. Molecular Biology of The Cell. Third edition, Garland, 1994. P655-683, P704-706, P715-716.