Human Research (Antioxidants, Inflammation and Disease)
Phillips, T., Childs, A. C., Dreon, D. M., Phinney, S., and Leeuwenburgh, C. (2003) A Dietary Supplement Attenuates IL-6 and CRP after Eccentric Exercise in Untrained Males. Med Sci Sports Exerc 35, 2032-2037
Childs A, Jacobs C, Kaminski T, Halliwell, B and C, Leeuwenburgh.Supplementation with vitamin C and N-acetyl-cysteine increases oxidative stress in humans after an acute muscle injury induced by eccentric exercise. Free Radic Biol Med, 2001;13(6):745-753.
Manary MJ, Leeuwenburgh C, Heinecke JW. Increased oxidative stress in kwashiorkor. J Pediatr. 2000 137 (3): 421-4.
Gokce N, Keaney JF Jr, Frei B, Holbrook M, Olesiak M, Zachariah BJ, Leeuwenburgh C, Heinecke JW, Vita JA. Long-term ascorbic acid administration reverses endothelial vasomotor dysfunction in patients with coronary artery disease.Circulation 1999 Jun 29;99(25):3234-40
Leeuwenburgh C, Rasmussen JE, Hsu FF, Mueller DM, Pennathur S, Heinecke JW. Mass spectrometric quantification of markers for protein oxidation by tyrosyl radical, copper, and hydroxyl radical in low density lipoprotein isolated from human atherosclerotic plaques. J Biol Chem 1997 Feb 7;272(6):3520-6
Leeuwenburgh C, Hardy MM, Hazen SL, Wagner P, Oh-ishi S, Steinbrecher UP, Heinecke JW. Reactive nitrogen intermediates promote low density lipoprotein oxidation in human atherosclerotic intima. J Biol Chem 1997 Jan 17;272(3):1433-6
Other Sites Investigating Oxidative Stress and Health in Humans
GALILEO
KRONOS